Synthetically produced THCA from CBGA:
THCA Production: THCA is typically produced from CBGA via the action of the enzyme THCA synthase, which can be done in vivo using plant-based methods or in engineered systems like yeast. Purely synthetic chemical routes to THCA, without using cannabis or biosynthetic pathways, are complex and not commonly practiced due to the efficiency and feasibility of biosynthetic methods.
CBGA Production: CBGA can be produced biosynthetically from olivetolic acid and geranyl pyrophosphate. While it is possible to chemically synthesize CBGA from non-cannabinoid precursors, this route is complex and less common compared to biosynthetic methods involving engineered organisms or extraction from cannabis.